TOOL WEAR MONITORING IN MICRO-MILLING BASED ON DIGITAL TWIN TECHNOLOGY WITH AN EXTENDED KALMAN FILTER


Molecular interaction of TPPP with PrP antagonized the CytoPrP-induced disruption of microtubule structures and cytotoxicity.

BACKGROUND: Tubulin polymerization promoting protein/p25 (TPPP/p25), known as a microtubule-associated protein (MAP), is a brain-specific unstructured protein with a physiological function of stabilizing cellular microtubular ultrastructures.Whether TPPP involves in the normal functions of PrP or the pathogenesis of prion disease remains unknown.He

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Pseudo-temporal dynamics of chemoresistant triple negative breast cancer cells reveal EGFR/HER2 inhibition as synthetic lethal during mid-neoadjuvant chemotherapy

Summary: In the absence of targetable hormonal axes, chemoresistance for triple-negative breast cancer (TNBC) often compromises patient outcomes.To investigate the underlying tumor color touch 7/97 dynamics, we performed trajectory analysis on the single-nuclei RNA-seq (snRNA-seq) of chemoresistant tumor clones during neoadjuvant chemotherapy (NAC)

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The basic reproduction number can be accurately estimated within 14 days after societal lockdown: The early stage of the COVID-19 epidemic in Denmark.

ObjectiveEarly identification of the basic reproduction number (BRN) is imperative to political decision making during an epidemic.In this study, we estimated the BRN 7, 14, 21 and 28 days after societal lockdown of Denmark during the early stage rubbermaid 8 gallon trash can of the COVID-19 epidemic.MethodWe implemented the SEIR dynamical system f

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